Paracetamol: About Paracetamol, Poisoning & Side Effects

paracetamol

What is Paracetamol actually?

Paracetamol, also known as Acetaminophen in some places. It is commonly used to reduce pain such as headaches and is also used to treat fever.

The word Paracetamol came from the word para-acetyl-amino-phenol and Acetaminophen came from the word para-acetylaminophenol.

Acetaminophen is over the counter medication for pain killer. You can buy Acetaminophen without doctor’s prescription. But always be sure and ask any professional medical health care before using or consume any drug.

Manufactured and marketed by Farmson Analgesics, paracetamol (acetaminophen) is a popular pain reliever and fever reducing medication. Acetaminophen may be used to treat a wide variety of ailments including headaches, muscle aches, arthritis, backaches, toothaches, fevers and colds. The drug alleviates pain in mild cases of arthritis but has no tangible effect on the underlying inflammation and swelling of the joint. Despite being in use for over 50 years in the United States, the exact mechanism of action in paracetamol is still not clearly understood by the scientific community.

For more info about Acetaminophen, Please visit the link below http://en.wikipedia.org/wiki/Paracetamol

 

Paracetamol Poisoning

Even the absolute most often encountered outcomes of Acetaminophen poisoning are nausea and nausea. These impacts usually arise within 2 4 hrs after this drug. Patients that suffer from these Signs Ought to Be taken for the hospital promptly to get your Therapy .

Due to the fact that it is widely prescribed and cheap to buy over-the-counter, paracetamol is commonly overdosed on. According to the British Medical Journal (BMJ), Acetaminophen is the most common medication used in overdose in the United Kingdom, accounting for nearly half of all poisoning admissions to hospital, and an estimated 100–200 deaths annually. Additionally, there are many deaths reported in users of paracetamol-based compounds, which are most commonly caused by acute liver failure.

Patients with Acetaminophen poisoning is treated using Acetylcysteine.
Please refer at the link below about Acetylcysteine :

http://en.wikipedia.org/wiki/Acetylcysteine

 Paracetamol Overdose

Have you suffered an overdose due to liver injury after taking paracetamol or other acetaminophen-containing medication? Though most people consider Acetaminophen to be extremely safe, this drug and others like it have long been associated with a serious risk of liver injury and even total liver failure. In fact, the U.S. Food & Drug Administration (FDA) has acted on several occasions to strengthen liver injury warnings on paracetamol and other acetaminophen-based drugs.

Free Acetaminophen Overdose Lawsuit Evaluation: If you or a loved one suffered an overdose after taking paracetamol-tablet, you should contact your docotor immediately. 

 Paracetamol Side Effects

All medications will usually have side effects. Side effects for Acetaminophen are rare, but you must always be precautions with any medicines you take. Paracetamol side effects are rare however there may be still a few minor adverse reactions may appear if you’re using paracetamol more that recommended dosage amounts.

Acetaminophen is well tolerated with much less adverse reactions. Long haul routine usage of Paracetamol escalates the chance of higher gastro intestinal problems like gut bleeding which can result in liver or kidney injury.

Liver Failure Reported in Acetaminophen Users

Exceeding the maximum daily dose of paracetamol (4 grams per day) can easily lead to serious liver damage, and even total liver failure, which can result in death. Despite a number of efforts to reduce the incidence of Acetaminophen related liver injuries, the extent of liver failure resulting from use of the drug reported in the medical literature continues to remain a serious public health problem.

Paracetamol causes liver injury when small amounts of acetaminophen are converted to a toxic metabolite. The toxic metabolite then binds with liver proteins to cause injuries on the cellular level. The amount of toxic metabolite manufactured and the ability of the liver to remove this metabolite before it binds to liver proteins affects the extent of liver injury caused by paracetamol.

From 1998 to 2003, acetaminophen-containing medications were the leading cause of acute liver failure in the U.S., with 48% of cases associated with accidental overdose. A 2007 study conducted by the Centers for Disease Control and Prevention (CDC) estimated that there are approximately 1,600 cases of acute liver failure annually nationwide, with acetaminophen based drugs being the most common etiology. Between 1990 and 1998, there were approximately 56,000 emergency room visits, 26,000 hospitalizations, and 458 deaths related to acetaminophen products like paracetamol.

 Liver Failure Symptoms

Signs and symptoms of paracetamol-induced liver damage may include:



  • discolored skin and eyes that appear yellowish
  • abdominal pain and swelling
  • itchy skin that doesn’t seem to go away
  • dark urine color
  • pale stool color
  • bloody or tar-colored stool
  • chronic fatigue
  • nausea
  • loss of appetite

Can cause acute liver toxicity at the following dosages (mg/kg body weight):

  • Less than 150 mg/kg – unlikely
  • More than 250 mg/kg – likely
  • More than 12 g total – potentially fatal

Paracetamol can cause serious and even fatal complications at approximately 150 mg/kg in many adults. Of course this varies from patient to patient, and depends on age, health, and medications taken in addition to Acetaminophen.

Do I Have a Paracetamol Overdose Lawsuit?

The Product Liability & Defective Drug Litigation Group at our law firm is an experienced team of trial lawyers that focus on the representation of plaintiffs inAcetaminophen Lawsuits. We are handling individual litigation nationwide and currently accepting new Paracetamol Overdose Lawsuits in all 50 states.

Free Acetaminophen Overdose Lawsuit Evaluation: Again, if you or a loved one suffered an overdose after taking Paracetamol, you should contact our law firm immediately.

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